A fatal bleeding event in an Alzheimer’s clinical trial participant may have been linked with the investigational anti-amyloid agent lecanemab, a case report suggested.

An experimental drug has slowed the rate of decline in memory and thinking in people with early Alzheimer’s disease in what is being described as a “historic moment” for dementia treatment.

FDG-PET is superior to amyloid PET imaging with the radiopharmaceutical florbetapir for assessing cognitive decline in patients with Alzheimer's disease or mild cognitive impairment. By Erik L. Ridley, AuntMinnie staff writer

There’s still a long way to go with both research into Alzheimer’s disease and AI tools to help detect it, but deep-learning approaches continue to show promise. Dave Pearson | Research | AI in Healthcare

A Dutch study estimates that without prevention strategies, 1 in 2 women and 1 in 3 men will be diagnosed with dementia/parkinsonism/stroke. From www.hospitalhealth.com.au

“The differences that we observed indicate the strong possibility that there are sex differences in the structural and functional connections in the brain, which may contribute to women’s increased risk for Alzheimer’s,” said Sepideh Shokouhi, at the Alzheimer’s Association International Conference in Los Angeles. Matt O'Connor | Molecular Imaging | www.healthimaging.com

ML Tool Detects Biomarker in Stroke Patients. RSNA/AAPM Symposium Focuses on Low-dose CT. Human Factors Impact Reporting of Safety Events. MRI-Based Technology Promising in Alzheimer’s. RSNA Online Series Targets Health Care Economics.

Microbleeds in the blood-brain barrier could lead to the infiltration of Alzheimer's disease-causing amyloid plaque, according to a University of Southern California. By AuntMinnie.com staff writers

New research guidelines for classifying whether individuals have Alzheimer's disease rely heavily on the use of biomarkers from imaging scans. The new framework was published in the April issue of Alzheimer's & Dementia: The Journal of the Alzheimer's Association by Wayne Forrest, AuntMinnie.com