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07
Feb

Perioperative Chemo Matches Multimodal Tx for Locally Advanced Esophageal/GEJ Cancer

A short course of perioperative chemotherapy for locally advanced esophageal/gastroesophageal junction (GEJ) cancer led to outcomes similar to those achieved with more intensive multimodal therapy, according to a randomised trial reported here.

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04
Feb

Bivalent Vaccine Slashes COVID Hospitalisations in Seniors

The bivalent COVID-19 booster targeting BA.4/5 showed high levels of protection against COVID-19 hospitalisation in older adults, an observational cohort study out of Israel showed.

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02
Feb

AI Passes U.S. Medical Licensing Exam

Two artificial intelligence (AI) programs, including ChatGPT, have passed the U.S. Medical Licensing Examination (USMLE), according to two recent papers.

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31
Jan

Obesity Linked to Brain Abnormalities in Kids

Children with overweight or obesity appeared to have abnormalities in the brain that could affect executive functioning, an analysis of data from the Adolescent Brain Cognitive Development (ABCD) Study showed.

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28
Jan

MRI-Targeted Biopsy for Prostate Cancer Reduces Risk of Overdiagnosis

Excluding systematic biopsy in favour of MRI-targeted biopsy in men with elevated prostate-specific antigen (PSA) levels reduced the probability of detecting clinically insignificant cancers, but at the risk of missing some clinically significant cancers and delaying their diagnosis.

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26
Jan

Scattered Brain Bleeds, Vasculitis in Alzheimer’s Trial Death

A fatal bleeding event in an Alzheimer’s clinical trial participant may have been linked with the investigational anti-amyloid agent lecanemab, a case report suggested.

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24
Jan

Optimising Treatment for Older Patients With HR + Low-Risk Breast Cancer

The time has come to revisit the practice of omitting adjuvant radiotherapy (RT) for older patients with early hormone receptor (HR)-positive breast cancer and instead consider a more individualised approach to RT and hormonal therapy, authors of a review article argued.

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21
Jan

Can Biomarkers Give Early Heads-Up on Immune Checkpoint Inhibitor Myocarditis?

In the quest to catch myocarditis earlier during immune checkpoint inhibitor (ICI) therapy for cancer, researchers have found a potential role for routinely measured biomarkers.

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19
Jan

Higher Brain Cancer Risk After CT Exam in Childhood

There has been an escalating risk of brain cancer associated with increasing radiation dose to the brain from CT examinations, a cohort study of more than 650,000 children and young adults indicated.

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17
Jan

Ultra-High-Res MRI Highlights Migraine Brain Changes

Powerful MRI scanners have detected white matter spots in the brain that appear to be associated with migraines, a researcher reported.

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