A fatal bleeding event in an Alzheimer’s clinical trial participant may have been linked with the investigational anti-amyloid agent lecanemab, a case report suggested.

The time has come to revisit the practice of omitting adjuvant radiotherapy (RT) for older patients with early hormone receptor (HR)-positive breast cancer and instead consider a more individualised approach to RT and hormonal therapy, authors of a review article argued.

In the quest to catch myocarditis earlier during immune checkpoint inhibitor (ICI) therapy for cancer, researchers have found a potential role for routinely measured biomarkers.

There has been an escalating risk of brain cancer associated with increasing radiation dose to the brain from CT examinations, a cohort study of more than 650,000 children and young adults indicated.

Powerful MRI scanners have detected white matter spots in the brain that appear to be associated with migraines, a researcher reported.

Drug overdose deaths in pregnancy or the postpartum period increased sharply in the U.S. in recent years, with the rise most pronounced at the start of the COVID-19 pandemic in 2020, researchers reported. From 2017 to 2020, overdose deaths in this population rose from 6.56 to 11.85 per 100,000 individuals, representing an 81% increase.

While a decision aid on preferences for colorectal cancer (CRC) screening aimed at older adults appeared to help improve knowledge, findings from a secondary analysis of a randomised trial did not show statistically significant differences in patient preferences between patients in varying states of health.

Whether it’s due to the side effects of local and systemic therapies, or the diagnosis itself, men with prostate cancer are at increased risk of mental distress and suicide. The mental health burden associated with a diagnosis and treatment is substantial, pointed out Zachary Klaassen, MD, of the Georgia Cancer Center at Augusta University.

Hospitalisation for status epilepticus seizures rose from 2010 to 2019, disproportionately affecting Black patients, U.S. inpatient data showed. The overall prevalence of status epilepticus hospitalisations more than doubled in that period, reported Gabriela Tantillo, MD, MPH, of Baylor College of Medicine in Houston.

Though studies evaluating the effects of posture on the absorption of drugs have been conducted, a systematised review revealed critical gaps in methodology.