It’s not just dense breasts that matter, researchers say – While recommendations for supplementary whole-breast ultrasounds were targeted to women with heterogeneously or extremely dense breasts, only a small proportion were at high risk of mammography screening failure, according to an observational study.

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Patients with primary mediastinal large B-cell lymphoma (PMBCL) in complete remission following standard chemoimmunotherapy may be able to safely avoid radiation therapy, despite negative findings from a noninferiority trial.

Standard pelvic chemoradiotherapy prior to surgery can be safely omitted in select patients with locally advanced rectal cancer whose tumours respond to neoadjuvant chemotherapy, findings from a large cooperative group trial demonstrated.

An “adaptive response” treatment strategy identified a subset of patients with HER2-positive early breast cancer who benefited from a chemotherapy-free treatment plan, according to new findings from the phase II PHERGain Trial.

Paediatric intracranial infections spiked recently and were associated with significant morbidity but remained rare, according to CDC researchers monitoring cases across the country.

For people with long COVID symptoms, hyperbaric oxygen therapy modestly improved one parameter of heart function in a small randomised trial.

A leadless dual-chamber pacemaker with bidirectional wireless communication turned in very promising short-term results in patients with standard indications for dual-chamber pacing, according to the Aveir DR i2i Study.

An investigational radionuclide therapy targeting prostate-specific membrane antigen (PSMA) achieved biochemical responses in 70% of patients with castration-resistant prostate cancer (CRPC), and prostate-specific antigen (PSA) reductions in all but one patient, enrolled in a small preliminary clinical trial.

Coronary anatomy and physiology both predicted early cardiac allograft vasculopathy (CAV) progression, according to a study that strengthens the case for advanced multimodal testing to improve early detection of a major contributor to allograft failure.