Staging locally advanced breast cancer patients with 18F-labeled fluorodeoxyglucose (FDG) PET-CT detected more distant metastases, and thus reduced the number of patients who received combined modality therapy, compared with conventional staging, a randomised trial showed.

An “adaptive response” treatment strategy identified a subset of patients with HER2-positive early breast cancer who benefited from a chemotherapy-free treatment plan, according to new findings from the phase II PHERGain Trial.

An investigational PET imaging agent, identified clear cell renal cell carcinoma (ccRCC) with high sensitivity and specificity, according to results from the phase III ZIRCON trial.

Immediate complete revascularization was non-inferior to staged complete revascularization in patients who presented with acute coronary syndrome (ACS) and multivessel disease, according to BIOVASC trial findings.

A new atrial fibrillation (Afib; AF) technology, pulsed field ablation, appears to eliminate abnormal heart rhythms in most patients for at least a year, a researcher reported here.

A short course of perioperative chemotherapy for locally advanced esophageal/gastroesophageal junction (GEJ) cancer led to outcomes similar to those achieved with more intensive multimodal therapy, according to a randomised trial reported here.

The osteoporosis drug denosumab (Prolia) not only stopped structural progression in patients with erosive osteoarthritis of the hand, but showed signs of reversing the damage, according to findings from a small trial.